If a nurse suspects IV infiltration of mechlorethamine hydrochloride during chemotherapy, what should be done immediately?

When a nurse suspects IV infiltration of mechlorethamine hydrochloride, a chemotherapy agent that can cause tissue damage if extravasated, the immediate step is to stop the infusion and leave the IV cannula in place. This action is crucial because it helps to prevent further infusion of the drug that could exacerbate the infiltration and potentially harm the surrounding tissues.

Leaving the IV cannula in place allows for the possibility of administering antidotes or other treatments if indicated, without needing to reinsert an IV line. It also enables healthcare providers to better assess the situation and implement further interventions appropriately.

While notifying the physician is essential to ensure that appropriate strategies are enacted promptly, stopping the infusion immediately is the priority. Other options, such as applying a heat compress or flushing the IV line with saline, may not be appropriate responses to infiltration and could delay necessary care.